The village of Castorano stands on the hills surrounding the Tronto valley, and has very ancient origins dating back to the time of the Italic peoples, in particular the Picenes.

Its history reveals a long list of conquerors: it was governed by the Romans between 296 and 297 BC, and after the fall of the Western Roman Empire, it was taken first by the Lombards and then by the Duchy of Spoleto, and later by the County formed at the time of Charlemagne.

In 1283 the Castorano district was sold to Ascoli, becoming a free commune in 1183. During the fourteenth and fifteenth centuries Castorano castle was raised to second level and tasked with watching over the Tronto River Valley and the territory of Offida, ally of Fermo, but already during the fifteenth century this defensive role lost its importance.

There were many ups and downs, and many acts of intolerance with attempts at rebellion, but Castorano remained under the control of Ascoli until the Unification of Italy.